Regulation of spermatogenesis and reproductive capacity by Igf3 in tilapia

A novel insulin-like growth factor ( igf3 ), which is exclusively expressed in the gonads, has been widely identified in fish species. Recent studies have indicated that Igf3 regulates spermatogonia proliferation and differentiation in zebrafish; however, detailed information on the role of this Igf...

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Veröffentlicht in:	Cellular and molecular life sciences : CMLS 2020-12, Vol.77 (23), p.4921-4938
Hauptverfasser:	Li, Minghui, Liu, Xingyong, Dai, Shengfei, Xiao, Hesheng, Qi, Shuangshuang, Li, Yibing, Zheng, Qiaoyuan, Jie, Mimi, Cheng, Christopher H. K., Wang, Deshou
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Androgens - pharmacology Animal models Animals Apoptosis Base Sequence Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Cell culture Cell cycle Cell Proliferation - drug effects CRISPR CRISPR-Cas Systems - genetics Differentiation Fish reproduction Gametocytes Gene Expression Regulation, Developmental - drug effects Gonads Growth factors Hatching In vivo methods and tests Insulin Insulin-like growth factors Life Sciences Male Meiosis Mice, Knockout Mutation - genetics Oreochromis niloticus Original Original Article Pluripotency Regulators Reproduction - drug effects Reproduction - genetics RNA, Messenger - genetics RNA, Messenger - metabolism Semen Signal Transduction - drug effects Signal Transduction - genetics Somatomedins - genetics Somatomedins - metabolism Sperm Spermatids Spermatocytes Spermatogenesis Spermatogenesis - drug effects Spermatogenesis - genetics Spermatogonia Spermatogonia - cytology Spermatogonia - drug effects Spermatogonia - metabolism Testes Testis - drug effects Testis - metabolism Tilapia Tilapia - genetics Tilapia - physiology Zebrafish
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