A multi-ancestry genome-wide association study in type 1 diabetes

Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by destruction of the pancreatic β-cells. Genome-wide association (GWAS) and fine mapping studies have been conducted mainly in European ancestry (EUR) populations. We performed a multi-ancestry GWAS to identify SNPs and HLA alleles asso...

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Veröffentlicht in:	Human molecular genetics 2024-05, Vol.33 (11), p.958-968
Hauptverfasser:	Michalek, Dominika A, Tern, Courtney, Zhou, Wei, Robertson, Catherine C, Farber, Emily, Campolieto, Paul, Chen, Wei-Min, Onengut-Gumuscu, Suna, Rich, Stephen S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age of Onset Alleles Black People - genetics Child Diabetes Mellitus, Type 1 - genetics Female Genetic Predisposition to Disease Genome-Wide Association Study Hispanic or Latino - genetics HLA Antigens - genetics HLA-DQ alpha-Chains - genetics Humans Male Original Polymorphism, Single Nucleotide White People - genetics
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