Dose-dependent effect of lamotrigine on quetiapine serum concentration in patients using instant release tablets

Purpose Lamotrigine was previously reported to reduce serum concentration of quetiapine. The aim of this study was to investigate whether lamotrigine dose or quetiapine formulation was of importance for the drug interaction. Methods Patients combining lamotrigine with quetiapine (cases) were include...

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Veröffentlicht in:	European journal of clinical pharmacology 2024-06, Vol.80 (6), p.839-845
Hauptverfasser:	Hole, Kristine, Lorentsen, Silje K, Nordby, Karoline L, Slettvik, Marie, Sørum, Ida TG, Molden, Espen, Haslemo, Tore
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Drug dosages Drug interaction Lamotrigine Pharmacology/Toxicology Quetiapine Tablets
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