A rare case report of bilateral vestibulopathy due to otosyphilis
Bilateral vestibulopathy is an important cause of imbalance. There are multiple etiologies of bilateral vestibulopathy (BVP), but reports of BVP due to otosyphilis are rare. A 39-year-old male was referred to our medical center due to vertigo, persistent dizziness and gait disturbance for 2 months....
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| Veröffentlicht in: | Medicine (Baltimore) 2024-05, Vol.103 (20), p.e38149 |
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| creator | Gu, Huanhuan Xu, Yixin Xu, Jin Zhuang, Jianhua |
| description | Bilateral vestibulopathy is an important cause of imbalance. There are multiple etiologies of bilateral vestibulopathy (BVP), but reports of BVP due to otosyphilis are rare.
A 39-year-old male was referred to our medical center due to vertigo, persistent dizziness and gait disturbance for 2 months.
Bilateral vestibulopathy due to otosyphilis was considered in this case, as confirmed through analyses of vestibular function, laboratory tests, and penicillin treatment.
The patient was was treated with a high dose of penicillin G (24 × 106 IU/d) for 14 days.
The patient's symptoms had improved greatly following treatment, with dizziness and gait disturbance having completely resolved at 3 months following hospital discharge.
Bilateral vestibulopathy should be considered when evaluating patients with acute or subacute persistent dizziness. Clinicians should also be aware of the potential for otosyphilis among patients who report BVP. |
| doi_str_mv | 10.1097/MD.0000000000038149 |
| format | Article |
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A 39-year-old male was referred to our medical center due to vertigo, persistent dizziness and gait disturbance for 2 months.
Bilateral vestibulopathy due to otosyphilis was considered in this case, as confirmed through analyses of vestibular function, laboratory tests, and penicillin treatment.
The patient was was treated with a high dose of penicillin G (24 × 106 IU/d) for 14 days.
The patient's symptoms had improved greatly following treatment, with dizziness and gait disturbance having completely resolved at 3 months following hospital discharge.
Bilateral vestibulopathy should be considered when evaluating patients with acute or subacute persistent dizziness. Clinicians should also be aware of the potential for otosyphilis among patients who report BVP.</description><identifier>ISSN: 0025-7974</identifier><identifier>ISSN: 1536-5964</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000038149</identifier><identifier>PMID: 38758873</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Adult ; Anti-Bacterial Agents - therapeutic use ; Bilateral Vestibulopathy - complications ; Bilateral Vestibulopathy - diagnosis ; Clinical Case Report ; Dizziness - diagnosis ; Dizziness - etiology ; Humans ; Male ; Penicillin G - administration & dosage ; Penicillin G - therapeutic use ; Syphilis - complications ; Syphilis - diagnosis ; Syphilis - drug therapy ; Vertigo - diagnosis ; Vertigo - etiology</subject><ispartof>Medicine (Baltimore), 2024-05, Vol.103 (20), p.e38149</ispartof><rights>Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.</rights><rights>Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c356t-5a4b345c431e35b9cb5cd76a8c1389781e64d0f46f3e08c5c753e28c5125226d3</cites><orcidid>0000-0001-9823-112 ; 0000-0001-9823-112X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098173/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098173/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38758873$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gu, Huanhuan</creatorcontrib><creatorcontrib>Xu, Yixin</creatorcontrib><creatorcontrib>Xu, Jin</creatorcontrib><creatorcontrib>Zhuang, Jianhua</creatorcontrib><title>A rare case report of bilateral vestibulopathy due to otosyphilis</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>Bilateral vestibulopathy is an important cause of imbalance. There are multiple etiologies of bilateral vestibulopathy (BVP), but reports of BVP due to otosyphilis are rare.
A 39-year-old male was referred to our medical center due to vertigo, persistent dizziness and gait disturbance for 2 months.
Bilateral vestibulopathy due to otosyphilis was considered in this case, as confirmed through analyses of vestibular function, laboratory tests, and penicillin treatment.
The patient was was treated with a high dose of penicillin G (24 × 106 IU/d) for 14 days.
The patient's symptoms had improved greatly following treatment, with dizziness and gait disturbance having completely resolved at 3 months following hospital discharge.
Bilateral vestibulopathy should be considered when evaluating patients with acute or subacute persistent dizziness. Clinicians should also be aware of the potential for otosyphilis among patients who report BVP.</description><subject>Adult</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bilateral Vestibulopathy - complications</subject><subject>Bilateral Vestibulopathy - diagnosis</subject><subject>Clinical Case Report</subject><subject>Dizziness - diagnosis</subject><subject>Dizziness - etiology</subject><subject>Humans</subject><subject>Male</subject><subject>Penicillin G - administration & dosage</subject><subject>Penicillin G - therapeutic use</subject><subject>Syphilis - complications</subject><subject>Syphilis - diagnosis</subject><subject>Syphilis - drug therapy</subject><subject>Vertigo - diagnosis</subject><subject>Vertigo - etiology</subject><issn>0025-7974</issn><issn>1536-5964</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUMtOwzAQtBCIlsIXICEfuaTYWb9yQhXlJbXiAmfLcRwalNbBTir170nVUh572ZV2ZnZ2ELqkZExJJm_m0zH5KVCUZUdoSDmIhGeCHaMhISlPZCbZAJ3F-EEIBZmyUzQAJblSEoZoMsHBBIetiQ4H1_jQYl_ivKpN64Kp8drFtsq72jemXWxw0TnceuxbHzfNoqqreI5OSlNHd7HvI_T2cP9695TMXh6f7yazxAIXbcINy4Fxy4A64Hlmc24LKYyyFFQmFXWCFaRkogRHlOVWcnBpP9CUp6koYIRud7pNly9dYd2q7f3pJlRLEzbam0r_3ayqhX73a037tBSV0Ctc7xWC_-z6v_SyitbVtVk530UNhAshUpJuobCD2uBjDK483KFEb9PX86n-n37Puvpt8cD5jhu-ANqPgCU</recordid><startdate>20240517</startdate><enddate>20240517</enddate><creator>Gu, Huanhuan</creator><creator>Xu, Yixin</creator><creator>Xu, Jin</creator><creator>Zhuang, Jianhua</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9823-112</orcidid><orcidid>https://orcid.org/0000-0001-9823-112X</orcidid></search><sort><creationdate>20240517</creationdate><title>A rare case report of bilateral vestibulopathy due to otosyphilis</title><author>Gu, Huanhuan ; Xu, Yixin ; Xu, Jin ; Zhuang, Jianhua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-5a4b345c431e35b9cb5cd76a8c1389781e64d0f46f3e08c5c753e28c5125226d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Bilateral Vestibulopathy - complications</topic><topic>Bilateral Vestibulopathy - diagnosis</topic><topic>Clinical Case Report</topic><topic>Dizziness - diagnosis</topic><topic>Dizziness - etiology</topic><topic>Humans</topic><topic>Male</topic><topic>Penicillin G - administration & dosage</topic><topic>Penicillin G - therapeutic use</topic><topic>Syphilis - complications</topic><topic>Syphilis - diagnosis</topic><topic>Syphilis - drug therapy</topic><topic>Vertigo - diagnosis</topic><topic>Vertigo - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gu, Huanhuan</creatorcontrib><creatorcontrib>Xu, Yixin</creatorcontrib><creatorcontrib>Xu, Jin</creatorcontrib><creatorcontrib>Zhuang, Jianhua</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gu, Huanhuan</au><au>Xu, Yixin</au><au>Xu, Jin</au><au>Zhuang, Jianhua</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A rare case report of bilateral vestibulopathy due to otosyphilis</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2024-05-17</date><risdate>2024</risdate><volume>103</volume><issue>20</issue><spage>e38149</spage><pages>e38149-</pages><issn>0025-7974</issn><issn>1536-5964</issn><eissn>1536-5964</eissn><abstract>Bilateral vestibulopathy is an important cause of imbalance. There are multiple etiologies of bilateral vestibulopathy (BVP), but reports of BVP due to otosyphilis are rare.
A 39-year-old male was referred to our medical center due to vertigo, persistent dizziness and gait disturbance for 2 months.
Bilateral vestibulopathy due to otosyphilis was considered in this case, as confirmed through analyses of vestibular function, laboratory tests, and penicillin treatment.
The patient was was treated with a high dose of penicillin G (24 × 106 IU/d) for 14 days.
The patient's symptoms had improved greatly following treatment, with dizziness and gait disturbance having completely resolved at 3 months following hospital discharge.
Bilateral vestibulopathy should be considered when evaluating patients with acute or subacute persistent dizziness. Clinicians should also be aware of the potential for otosyphilis among patients who report BVP.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>38758873</pmid><doi>10.1097/MD.0000000000038149</doi><orcidid>https://orcid.org/0000-0001-9823-112</orcidid><orcidid>https://orcid.org/0000-0001-9823-112X</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Wolters Kluwer Open Health; MEDLINE; DOAJ Directory of Open Access Journals; IngentaConnect Free/Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Anti-Bacterial Agents - therapeutic use Bilateral Vestibulopathy - complications Bilateral Vestibulopathy - diagnosis Clinical Case Report Dizziness - diagnosis Dizziness - etiology Humans Male Penicillin G - administration & dosage Penicillin G - therapeutic use Syphilis - complications Syphilis - diagnosis Syphilis - drug therapy Vertigo - diagnosis Vertigo - etiology |
| title | A rare case report of bilateral vestibulopathy due to otosyphilis |
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