MultiplexMS: A Mass Spectrometry-Based Multiplexing Strategy for Ultra-High-Throughput Analysis of Complex Mixtures

High-throughput chemical analysis of natural product mixtures lags behind developments in genome sequencing technologies and laboratory automation, leading to a disconnect between library-scale chemical and biological profiling that limits new molecule discovery. Here, we report a new orthogonal sam...

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Veröffentlicht in:	Analytical chemistry (Washington) 2023-08, Vol.95 (32), p.11908-11917
Hauptverfasser:	Recchia, Michael J. J., Baumeister, Tim U. H., Liu, Dennis Y., Linington, Roger G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Automation Bioactive compounds Biological activity Biological Products Chemical analysis Chemistry Drug Discovery Gene sequencing Genomes Mass Spectrometry Mass spectroscopy Metabolites Mixtures Multiplexing Natural products Open source software Scientific imaging Software Technology
Online-Zugang:	Volltext
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