Parkinson’s Disease is Predominantly a Genetic Disease

The discovery of a pathogenic variant in the alpha-synuclein (SNCA) gene in the Contursi kindred in 1997 indisputably confirmed a genetic cause in a subset of Parkinson’s disease (PD) patients. Currently, pathogenic variants in one of the seven established PD genes or the strongest known risk factor...

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Veröffentlicht in:	Journal of Parkinson's disease 2024-01, Vol.14 (3), p.467-482
Hauptverfasser:	Lim, Shen-Yang, Klein, Christine
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Disease Epigenetics Etiology Genetic disorders LRRK2 protein Movement disorders Neurodegenerative diseases Parkinson's disease Position Paper: For/Against Risk factors Synuclein
Online-Zugang:	Volltext
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