Pervasive environmental chemicals impair oligodendrocyte development

Exposure to environmental chemicals can impair neurodevelopment, and oligodendrocytes may be particularly vulnerable, as their development extends from gestation into adulthood. However, few environmental chemicals have been assessed for potential risks to oligodendrocytes. Here, using a high-throug...

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Veröffentlicht in:	Nature neuroscience 2024-05, Vol.27 (5), p.836-845
Hauptverfasser:	Cohn, Erin F., Clayton, Benjamin L. L., Madhavan, Mayur, Lee, Kristin A., Yacoub, Sara, Fedorov, Yuriy, Scavuzzo, Marissa A., Paul Friedman, Katie, Shafer, Timothy J., Tesar, Paul J.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/2596/1705 631/378/2606 Animal Genetics and Genomics Animals Apoptosis Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Cell death Cell Differentiation - drug effects Cells, Cultured Chemicals Children Chloride Consumer products Cytotoxicity Environmental Pollutants - toxicity Epidemiology Female Fibroblasts Flame retardants Flame Retardants - toxicity Hazard identification Household products Humans Mice Mice, Inbred C57BL Neurobiology Neurodevelopment Neurodevelopmental disorders Neurosciences Oligodendrocytes Oligodendroglia - drug effects Organoids Organophosphates PCB Polychlorinated biphenyls R&D Research & development Toxicity
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