Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib

Snakebite envenoming is a neglected tropical disease that causes substantial mortality and morbidity globally. The venom of African spitting cobras often causes permanent injury via tissue-destructive dermonecrosis at the bite site, which is ineffectively treated by current antivenoms. To address th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2024-05, Vol.121 (19), p.e2315597121
Hauptverfasser: Bartlett, Keirah E, Hall, Steven R, Rasmussen, Sean A, Crittenden, Edouard, Dawson, Charlotte A, Albulescu, Laura-Oana, Laprade, William, Harrison, Robert A, Saviola, Anthony J, Modahl, Cassandra M, Jenkins, Timothy P, Wilkinson, Mark C, Gutiérrez, José María, Casewell, Nicholas R
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!