DNA glycosylases provide antiviral defence in prokaryotes

Bacteria have adapted to phage predation by evolving a vast assortment of defence systems 1 . Although anti-phage immunity genes can be identified using bioinformatic tools, the discovery of novel systems is restricted to the available prokaryotic sequence data 2 . Here, to overcome this limitation,...

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Veröffentlicht in:	Nature (London) 2024-05, Vol.629 (8011), p.410-416
Hauptverfasser:	Hossain, Amer A., Pigli, Ying Z., Baca, Christian F., Heissel, Søren, Thomas, Alexis, Libis, Vincent K., Burian, Ján, Chappie, Joshua S., Brady, Sean F., Rice, Phoebe A., Marraffini, Luciano A.
Format:	Artikel
Sprache:	eng
Schlagworte:	45/22 45/23 45/29 631/326/1321 631/326/41/2529 82/58 Bacteria Bases (nucleic acids) Cloning Defense Deoxyribonucleic acid DNA DNA glycosylase E coli Genes Genomes Humanities and Social Sciences Immunity Infections Metagenomics multidisciplinary Phages Predation Prokaryotes Science Science (multidisciplinary)
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