New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization

New 3-substituted oxindole derivatives were designed and synthesized as antiproliferative agents. The antiproliferative activity of compounds 6a–j was evaluated against 60 NCI cell lines. Among these tested compounds, compounds 6f and 6g showed remarkable antiproliferative activity, specifically aga...

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Veröffentlicht in:	Molecular diversity 2024-04, Vol.28 (2), p.563-580
Hauptverfasser:	Ezelarab, Hend A. A., Ali, Taha F. S., Abbas, Samar H., Sayed, Ahmed M., Beshr, Eman A. M., Hassan, Heba A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Breast cancer Life Sciences Organic Chemistry Original Original Article Pharmacy Polymer Sciences Polymerization
Online-Zugang:	Volltext
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