Memory, mood and associated neuroanatomy in individuals with steroid sulphatase deficiency (X‐linked ichthyosis)

Steroid sulphatase (STS) cleaves sulphate groups from steroid hormones, and steroid (sulphate) levels correlate with mood and age‐related cognitive decline. In animals, STS inhibition or deletion of the associated gene, enhances memory/neuroprotection and alters hippocampal neurochemistry. Little is...

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Veröffentlicht in:	Genes, brain and behavior brain and behavior, 2024-06, Vol.23 (3), p.e12893-n/a
Hauptverfasser:	Wren, Georgina H., Flanagan, Jessica, Underwood, Jack F. G., Thompson, Andrew R., Humby, Trevor, Davies, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Affect Aged Anatomy Brain architecture Cognitive ability dehydroepiandrosterone sulphate Female Gene deletion Genetic diversity globus pallidus Hippocampus Humans Ichthyosis Ichthyosis, X-Linked - genetics Male Memory Middle Aged Mood Neuroprotection online survey Original Steroid hormones Steroids Steryl-Sulfatase - genetics Xp22.31
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