Lutetium-177 Labelled Anti-PSMA Monoclonal Antibody (Lu-TLX591) Therapy for Metastatic Prostate Cancer: Treatment Toxicity and Outcomes

Introduction Whilst prostate cancer is the fourth most common cancer globally, effective therapies for patients with advanced disease are lacking. In recent years, interest in using theranostic agents to treat castrate-resistant prostate cancer (CRPC) and metastatic prostate cancer has emerged. Lu-T...

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Veröffentlicht in:	Molecular diagnosis & therapy 2024-05, Vol.28 (3), p.291-299
Hauptverfasser:	Nguyen, Hanh, Hird, Kathryn, Cardaci, Joe, Smith, Steven, Lenzo, Nat P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Androgens Anemia Anorexia Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - therapeutic use Antigens Antigens, Surface - immunology Biomedical and Life Sciences Biomedicine Blood tests Cancer Research Cancer therapies Clinical trials Drug dosages Eating disorders Effectiveness Electronic health records Electronic medical records Glutamate Carboxypeptidase II - antagonists & inhibitors Glutamate Carboxypeptidase II - immunology Hematology Human Genetics Humans Laboratory Medicine Leukopenia Ligands Lutetium Lutetium - adverse effects Lutetium - therapeutic use Lymphopenia Male Medical prognosis Medical records Metastases Metastasis Middle Aged Molecular Medicine Monoclonal antibodies Neoplasm Metastasis Neutropenia Oncology Original Original Research Article Patients Peptides Pharmaceuticals Pharmacotherapy Positron emission Positron emission tomography Precision medicine Prostate cancer Prostate-specific antigen Prostate-Specific Antigen - blood Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Prostatic Neoplasms, Castration-Resistant - drug therapy Prostatic Neoplasms, Castration-Resistant - pathology Radiochemistry Radioisotopes Radioisotopes - adverse effects Radioisotopes - therapeutic use Radiology Radiopharmaceuticals - adverse effects Radiopharmaceuticals - therapeutic use Retrospective Studies Side effects Thrombocytopenia Toxicity Treatment Outcome
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