Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in mice

Connexin43 (Cx43) is the most abundant gap junction protein present in the mesenchymal lineage. In mature adipocytes, Cx43 mediates white adipose tissue (WAT) beiging in response to cold exposure and maintains the mitochondrial integrity of brown adipose tissue (BAT). We found that genetic deletion...

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Veröffentlicht in:	JCI insight 2024-02, Vol.9 (6)
Hauptverfasser:	Lee, Seung-Yon, Fontana, Francesca, Sugatani, Toshifumi, Portales Castillo, Ignacio, Leanza, Giulia, Coler-Reilly, Ariella, Civitelli, Roberto
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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