First trimester maternal tryptophan metabolism and embryonic and fetal growth: the Rotterdam Periconceptional Cohort (Predict Study)

What is the association between first trimester maternal tryptophan (TRP) metabolites and embryonic and fetal growth? Higher 5-hydroxytryptophan (5-HTP) concentrations are associated with reduced embryonic growth and fetal growth and with an increased risk of small-for-gestational age (SGA), while h...

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Veröffentlicht in:	Human reproduction (Oxford) 2024-05, Vol.39 (5), p.912-922
Hauptverfasser:	van Zundert, Sofie K M, van Egmond, Nina C M, van Rossem, Lenie, Willemsen, Sten P, Griffioen, Pieter H, van Schaik, Ron H N, Mirzaian, Mina, Steegers-Theunissen, Régine P M
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Hydroxytryptophan Adult Cohort Studies Embryonic Development Female Fetal Development Fetal Growth Retardation - blood Fetal Growth Retardation - metabolism Humans Infant, Newborn Infant, Small for Gestational Age Kynurenine - blood Kynurenine - metabolism Netherlands Original Pregnancy Pregnancy Trimester, First - blood Prospective Studies Tryptophan - blood Tryptophan - metabolism Ultrasonography, Prenatal
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