Deficient expression of class-I HLA in some cases of acute leukemia

Leukemic cells from the blood and marrow of 25 cases of newly diagnosed acute leukemia were presented as target cells to alloreactive effector cells from unrelated normal donors in cell-mediated cytotoxicity assays. In three cases the leukemic targets were poorly killed relative to nonleukemic, HLA-...

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Veröffentlicht in:	Cancer Immunology Immunotherapy 1984-01, Vol.18 (2), p.91-100
Hauptverfasser:	ELKINS, W. L, PICKARD, A, PIERSON, G. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Biological and medical sciences Bone Marrow - immunology Cells, Cultured Child Cytotoxicity, Immunologic Fluorescent Antibody Technique Hematologic and hematopoietic diseases HLA Antigens - analysis Humans Leukemia - immunology Leukemia - pathology Leukemia, Lymphoid - immunology Leukemia, Myeloid, Acute - immunology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphocyte Culture Test, Mixed Medical sciences Original
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