Effect on natural killer and antibody-dependent cellular cytotoxicity of adjuvant cytotoxic chemotherapy including melphalan in breast cancer

Natural killer (NK) cell activity and antibody-dependent (K) cell activity were studied sequentially in 30 patients with early node-positive breast cancer entered into an adjuvant chemotherapy trial. The drugs used were melphalan, and melphalan with methotrexate, given for 12 months. Estimations wer...

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Veröffentlicht in:	Cancer Immunology Immunotherapy 1983-12, Vol.16 (2), p.98-100
Hauptverfasser:	MACKAY, I. R, GOODYEAR, M. D. E, RIGLAR, C, PENSCHOW, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody-Dependent Cell Cytotoxicity - drug effects Antineoplastic agents Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - immunology Chemotherapy Cytotoxicity, Immunologic - drug effects Drug Therapy, Combination Female Humans Killer Cells, Natural - drug effects Killer Cells, Natural - immunology Long-Term Care Medical sciences Melphalan - therapeutic use Methotrexate - therapeutic use Original Pharmacology. Drug treatments Recurrence
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