The difference between 5-fluorouracil and melphalan in their ability to promote antitumor immune response against MOPC-315 plasmacytoma

The anticancer chemotherapeutic drugs melphalan (L-phenylalanine mustard; L-PAM), 5-fluorouracil (5-FU), methotrexate (MTX), and daunorubicin (DAU) were tested for their toxic activity against MOPC-315 tumor cells in vitro. L-PAM, 5-FU, and DAU had a marked toxic effect whereas MTX did not affect th...

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Veröffentlicht in:	Cancer Immunology Immunotherapy 1986-05, Vol.22 (1), p.43-48
Hauptverfasser:	BEN-EFRAIM, S, SHOVAL, S, OPHIR, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - pharmacology Animals Biological and medical sciences Concanavalin A - pharmacology Cytotoxicity, Immunologic - drug effects Fluorouracil - pharmacology Immunomodulators Lymphocyte Activation - drug effects Medical sciences Melphalan - pharmacology Mice Mice, Inbred BALB C Myeloma Proteins - immunology Original Pharmacology. Drug treatments Phytohemagglutinins - pharmacology Plasmacytoma - drug therapy Plasmacytoma - immunology Plasmacytoma - physiopathology Spleen - immunology T-Lymphocytes, Regulatory - immunology
Online-Zugang:	Volltext
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