Granulocyte/macrophage-colony-stimulating factor released by adenovirally transduced CT26 cells leads to the local expression of macrophage inflammatory protein 1α and accumulation of dendritic cells at vaccination sites in vivo

Antigen presenting cells (APC) play an essential role in the generation of tumor-specific immune responses. Dendritic cells are the most potent of APC, capable of activating both antigen-specific CD4 + and CD8 + T cells. Previously, we have described how vaccination of mice with irradiated tumor cel...

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Veröffentlicht in:Cancer Immunology, Immunotherapy Immunotherapy, 1999-06, Vol.48 (2-3), p.123-131
Hauptverfasser: KIELIAN, T, NAGAI, E, IKUBO, A, RASMUSSEN, C. A, SUZUKI, T
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Sprache:eng
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