αvβ3 expression on blood vessels and melanoma cells in primary lesions; differential association with tumor progression and clinical prognosis

The α v β 3 integrin has emerged as a key mediator in angiogenesis. Its role in tumor-induced angiogenesis is supported by its up-regulation in vivo in the vasculature of a number of different types of carcinoma. The potential clinical significance of α v β 3 expression on blood vessels in carcinoma...

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Veröffentlicht in:Cancer Immunology, Immunotherapy : CII Immunotherapy : CII, 2000-07, Vol.49 (6), p.314-318
Hauptverfasser: KAGESHITA, T, HAMBY, C. V, HIRAI, S, KIMURA, T, ONO, T, FERRONE, S
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Sprache:eng
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