A phase I/II trial of oxidized autologous tumor vaccines during the watch and wait phase of chronic lymphocytic leukemia

Based on their activity in patients with advanced stage chronic lymphocytic leukemia (CLL), a phase I/II study was designed to evaluate the feasibility, safety, and efficacy of autologous vaccines made from oxidized tumor cells in patients with earlier stage CLL, and to determine an optimal schedule...

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Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2005-07, Vol.54 (7), p.635-646
Hauptverfasser:	SPANER, David E, HAMMOND, Caitlin, MENA, Jenny, FODEN, Cindy, DEABREU, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens, CD - immunology Antigens, CD - metabolism Antineoplastic agents B7-1 Antigen - immunology B7-1 Antigen - metabolism B7-2 Antigen Biological and medical sciences Cancer Vaccines - therapeutic use Feasibility Studies Female Hematologic and hematopoietic diseases Humans Immunotherapy Leukemia, Lymphocytic, Chronic, B-Cell - immunology Leukemia, Lymphocytic, Chronic, B-Cell - therapy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Membrane Glycoproteins - immunology Membrane Glycoproteins - metabolism Middle Aged Original Pharmacology. Drug treatments T-Lymphocytes - immunology T-Lymphocytes, Cytotoxic - immunology Transplantation, Autologous Tumor Cells, Cultured
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