Th2/Th1 switch induced by a single low dose of cyclophosphamide in a rat metastatic lymphoma model

Cyclophosphamide (Cy) is an alkylating agent widely used in cancer chemotherapy. It has a bimodal effect on the immune system, depending on the dose and schedule of administration. We have previously demonstrated that a single low dose of Cy has an antimetastatic effect, achieved through immunomodul...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2002-01, Vol.50 (11), p.588-596
Hauptverfasser:	MATAR, Pablo, ROZADOS, Viviana R, GERVASONI, Silvia I, SCHAROVSKY, O. Graciela
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - administration & dosage Adjuvants, Immunologic - therapeutic use Animals Antineoplastic agents Antineoplastic Agents, Alkylating - administration & dosage Antineoplastic Agents, Alkylating - therapeutic use Biological and medical sciences Cancer therapies Chemotherapy Cyclophosphamide - administration & dosage Cyclophosphamide - therapeutic use Cytokines Cytotoxicity Female Immune system Interferon-gamma - biosynthesis Interferon-gamma - immunology Interleukin-10 - biosynthesis Interleukin-10 - immunology Interleukin-2 - biosynthesis Interleukin-2 - immunology Lymphatic Metastasis Lymphoma Lymphoma - drug therapy Lymphoma - immunology Lymphoma - pathology Male Medical sciences Metastasis Original Pharmacology. Drug treatments Rats Spleen Th1 Cells - immunology Th2 Cells - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!