Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: preclinical results and outcome of a first clinical phase I/II trial

In this study we have presented in vitro data and results of a preliminary clinical trial using dendritic cells (DC) in patients with progressive metastatic renal cell carcinoma. DC precursor cells were obtained from peripheral blood mononuclear cells (PBMC). DC were pulsed with autologous tumor cel...

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Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2002-12, Vol.51 (11-12), p.637-644
Hauptverfasser:	MÄRTEN, Angela, FLIEGER, Dimitri, KRIZEK, Ludmila, FABER, Cora, VON RUECKER, Alexander, MÜLLER, Stefan, SAUERBRUCH, Tilman, SCHMIDT-WOLF, Ingo G. H, RENOTH, Sabine, WEINECK, Silvia, ALBERS, Peter, COMPES, Markus, SCHÖTTKER, Björn, ZISKE, Carsten, ENGELHART, Steffen, HANFLAND, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Biological and medical sciences Carcinoma, Renal Cell - immunology Carcinoma, Renal Cell - secondary Carcinoma, Renal Cell - therapy Cytokines - blood Cytotoxicity, Immunologic Dendritic Cells - immunology Female Hemocyanins - immunology Humans Hypersensitivity, Delayed - etiology Immunotherapy Kidney Neoplasms - immunology Kidney Neoplasms - therapy Male Medical sciences Middle Aged Original Pharmacology. Drug treatments Vaccination
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