Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display

Serological cloning of tumor-associated antigens (TAAs) using patient autoantibodies and tumor cDNA expression libraries (SEREX) has identified a wide array of tumor proteins eliciting B-cell responses in patients. However, alternative cloning strategies with the possibility of high throughput analy...

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Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2004-05, Vol.53 (5), p.431-438
Hauptverfasser:	FOSSA, Alexander, ALSØE, Lene, CRAMERI, Reto, FUNDERUD, Steinar, GAUDERNACK, Gustav, SMELAND, Erlend B
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antigens Antigens, Neoplasm - genetics Antigens, Neoplasm - immunology Antigens, Surface Antineoplastic agents Bacteriophage M13 Biological and medical sciences Blotting, Western Cell cycle Cloning Cloning, Molecular DNA, Complementary - genetics Enzyme-Linked Immunosorbent Assay Gene Library Humans Immunoglobulin G - immunology Immunotherapy Lymphatic Metastasis Male Medical sciences Membrane Proteins - immunology Original Patients Peptide Library Pharmacology. Drug treatments Prostate cancer Prostatic Neoplasms - genetics Proteins Recombinant Proteins - immunology Recombinant Proteins - isolation & purification Recombinant Proteins - metabolism Serology Signal transduction Testis - immunology Tumors Vaccines
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