Serum immunoglobulin and the threshold of Fc receptor-mediated immune activation

Antibodies can mediate immune recruitment or clearance of immune complexes through the interaction of their Fc domain with cellular Fc receptors. Clustering of antibodies is a key step in generating sufficient avidity for efficacious receptor recognition. However, Fc receptors may be saturated with...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochimica et biophysica acta. General subjects 2023-11, Vol.1867 (11), p.130448-130448, Article 130448
Hauptverfasser:	Bauer-Smith, Hannah, Sudol, Abigail S.L., Beers, Stephen A., Crispin, Max
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody structure Effector functions Fc receptors Glycosylation Immunoglobulin Immunoglobulin Fc Fragments - metabolism Immunoglobulin G - metabolism Receptors, Fc Receptors, IgG - metabolism Therapeutic antibodies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!