CD8⁺ tumor-infiltrating lymphocytes predict favorable prognosis in malignant pleural mesothelioma after resection

Defects in human leukocyte antigen (HLA) class I expression may allow tumor cells to escape immune recognition. T cell infiltration is associated with a good prognosis in many cancers. However, the role of HLA class I expression and tumor-infiltrating lymphocytes (TILs) in malignant pleural mesothel...

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Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2010-10, Vol.59 (10), p.1543-1549
Hauptverfasser:	Yamada, Noriyuki, Oizumi, Satoshi, Kikuchi, Eiki, Shinagawa, Naofumi, Konishi-Sakakibara, Jun, Ishimine, Atsushi, Aoe, Keisuke, Gemba, Kenichi, Kishimoto, Takumi, Torigoe, Toshihiko, Nishimura, Masaharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens Antineoplastic agents Biological and medical sciences Cancer Research CD8-Positive T-Lymphocytes - immunology Chemotherapy Cloning Female HLA class I Humans Immunohistochemistry Immunology Immunotherapy Leukocytes Lymphocytes Lymphocytes, Tumor-Infiltrating - immunology Male Malignant pleural mesothelioma Medical prognosis Medical sciences Medicine Medicine & Public Health Mesothelioma Mesothelioma - immunology Mesothelioma - physiopathology Middle Aged Neoplasm Staging Oncology Original Original Article Patients Pharmacology. Drug treatments Pleural Neoplasms - immunology Pleural Neoplasms - physiopathology Pneumology Pneumonectomy Prognosis Survival analysis Tumor-infiltrating lymphocytes (TIL) Tumors of the respiratory system and mediastinum
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