Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique
The presence of circulating antineuronal antibodies has been associated with paraneoplastic neurological syndromes (PNS). Ri antibodies are often associated with lung or breast cancer, but the prevalence of such antibodies in large cancer materials is largely unknown. We used a highly sensitive immu...
Gespeichert in:
| Veröffentlicht in: | Cancer Immunology, Immunotherapy Immunotherapy, 2006-10, Vol.55 (10), p.1280-1284 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1284 |
|---|---|
| container_issue | 10 |
| container_start_page | 1280 |
| container_title | Cancer Immunology, Immunotherapy |
| container_volume | 55 |
| creator | KNUDSEN, Anette MONSTAD, Sissel E DORUM, Anne LØNNING, Per E SALVESEN, Helga B DRIVSHOLM, Lars AARSETH, Jan H VEDELER, Christian A |
| description | The presence of circulating antineuronal antibodies has been associated with paraneoplastic neurological syndromes (PNS). Ri antibodies are often associated with lung or breast cancer, but the prevalence of such antibodies in large cancer materials is largely unknown. We used a highly sensitive immunoprecipitation assay to study the level of Ri antibodies in blood samples from 200 patients with small cell lung cancer (SCLC), 253 patients with breast cancer and 557 patients with ovarian cancer. Two hundred blood donors and six Ri positive PNS patients served as controls. The recombinant antigen used in the immunoprecipitation assay was radiolabeled by a coupled in vitro transcription and translation (ITT) technique, enabling low levels of antibodies to be detected. None of the blood donors contained Ri antibodies, whereas all of the sera from the PNS patients were positive. Ri antibodies were present in 4.5% of the patients with SCLC, 0.8% of the patients with breast cancer and in 0.2% of the patients with ovarian cancer. Retesting of the Ri positive samples with immunofluorescense and immune blot showed that the immunoprecipitation technique was more sensitive than the other immune assays. Ri antibodies were not associated with PNS in the patients with breast or ovarian cancer. Neurological data were not available for the SCLC patients, but in these, Ri antibodies were not associated with survival. |
| doi_str_mv | 10.1007/s00262-006-0121-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11030605</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68590151</sourcerecordid><originalsourceid>FETCH-LOGICAL-c486t-ac3cd46f7b25f15aaa59f27c5ed2989fa451a91b6a7c30dc68690ba8737a5b6e3</originalsourceid><addsrcrecordid>eNqFkk2LFDEQhoMo7rj6A7xIEPRkayXppDunRRa_YEEQPYfqdHonS3cyJumRvfnTzTCDq168JKHy1Et9vIQ8ZfCaAXRvMgBXvAFQDTDOGn6PbFgraqSX7D7ZgGih6QDaM_Io55v64KD1Q3LGVMu1YO2G_PziKYbihzh6l6kPdIfFu1Ay_eHLlg7JYS6vaNxj8hhoTDQvOM_UunrMa7imFoN1iY6uuLT44EY63FKk2YXsi9876pdlDXGXnPU7X6p8DLQ4uw3---oekwcTztk9Od3n5Nv7d18vPzZXnz98unx71di2V6VBK-zYqqkbuJyYRESpJ95Z6Uauez1hKxlqNijsrIDRql5pGLDvRIdyUE6ck4uj7m4dFjfa2mLC2eySXzDdmoje_P0T_NZcx71hDAQokFXh5UkhxVp4Lmbx-TAGDC6u2aheamCS_RfkwAUTWlXw-T_gTVxTqGMwnAl5wLoKsSNkU8w5uel3zQzMwQbmaANTbWAONjC85jz7s9m7jNPeK_DiBGC2OE-p7tDnO67TiguuxC-OSL2a</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>213502317</pqid></control><display><type>article</type><title>Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique</title><source>Wiley Free Content</source><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><source>IngentaConnect Free/Open Access Journals</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>KNUDSEN, Anette ; MONSTAD, Sissel E ; DORUM, Anne ; LØNNING, Per E ; SALVESEN, Helga B ; DRIVSHOLM, Lars ; AARSETH, Jan H ; VEDELER, Christian A</creator><creatorcontrib>KNUDSEN, Anette ; MONSTAD, Sissel E ; DORUM, Anne ; LØNNING, Per E ; SALVESEN, Helga B ; DRIVSHOLM, Lars ; AARSETH, Jan H ; VEDELER, Christian A</creatorcontrib><description>The presence of circulating antineuronal antibodies has been associated with paraneoplastic neurological syndromes (PNS). Ri antibodies are often associated with lung or breast cancer, but the prevalence of such antibodies in large cancer materials is largely unknown. We used a highly sensitive immunoprecipitation assay to study the level of Ri antibodies in blood samples from 200 patients with small cell lung cancer (SCLC), 253 patients with breast cancer and 557 patients with ovarian cancer. Two hundred blood donors and six Ri positive PNS patients served as controls. The recombinant antigen used in the immunoprecipitation assay was radiolabeled by a coupled in vitro transcription and translation (ITT) technique, enabling low levels of antibodies to be detected. None of the blood donors contained Ri antibodies, whereas all of the sera from the PNS patients were positive. Ri antibodies were present in 4.5% of the patients with SCLC, 0.8% of the patients with breast cancer and in 0.2% of the patients with ovarian cancer. Retesting of the Ri positive samples with immunofluorescense and immune blot showed that the immunoprecipitation technique was more sensitive than the other immune assays. Ri antibodies were not associated with PNS in the patients with breast or ovarian cancer. Neurological data were not available for the SCLC patients, but in these, Ri antibodies were not associated with survival.</description><identifier>ISSN: 0340-7004</identifier><identifier>EISSN: 1432-0851</identifier><identifier>EISSN: 1365-2567</identifier><identifier>DOI: 10.1007/s00262-006-0121-2</identifier><identifier>PMID: 16429314</identifier><identifier>CODEN: CIIMDN</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Antibodies - blood ; Antigens, Neoplasm - immunology ; Antineoplastic agents ; Biological and medical sciences ; Blotting, Western ; Breast Neoplasms - blood ; Breast Neoplasms - immunology ; Breast Neoplasms - mortality ; Carcinoma, Small Cell - blood ; Carcinoma, Small Cell - immunology ; Female ; Fluorescent Antibody Technique ; Humans ; Immunoblotting ; Immunoprecipitation - methods ; Immunotherapy ; Lung cancer ; Lung Neoplasms - blood ; Lung Neoplasms - immunology ; Lung Neoplasms - mortality ; Medical sciences ; Neoplasms - blood ; Neoplasms - immunology ; Neoplasms - mortality ; Nerve Tissue Proteins - immunology ; Neuro-Oncological Ventral Antigen ; Original ; Ovarian Neoplasms - blood ; Ovarian Neoplasms - immunology ; Ovarian Neoplasms - mortality ; Paraneoplastic Syndromes - blood ; Paraneoplastic Syndromes - diagnosis ; Paraneoplastic Syndromes - immunology ; Pharmacology. Drug treatments ; Pneumology ; RNA-Binding Proteins - immunology ; Sensitivity and Specificity ; Survival Analysis ; Tumors of the respiratory system and mediastinum</subject><ispartof>Cancer Immunology, Immunotherapy, 2006-10, Vol.55 (10), p.1280-1284</ispartof><rights>2006 INIST-CNRS</rights><rights>Springer-Verlag 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c486t-ac3cd46f7b25f15aaa59f27c5ed2989fa451a91b6a7c30dc68690ba8737a5b6e3</citedby><cites>FETCH-LOGICAL-c486t-ac3cd46f7b25f15aaa59f27c5ed2989fa451a91b6a7c30dc68690ba8737a5b6e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11030605/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11030605/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17962326$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16429314$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KNUDSEN, Anette</creatorcontrib><creatorcontrib>MONSTAD, Sissel E</creatorcontrib><creatorcontrib>DORUM, Anne</creatorcontrib><creatorcontrib>LØNNING, Per E</creatorcontrib><creatorcontrib>SALVESEN, Helga B</creatorcontrib><creatorcontrib>DRIVSHOLM, Lars</creatorcontrib><creatorcontrib>AARSETH, Jan H</creatorcontrib><creatorcontrib>VEDELER, Christian A</creatorcontrib><title>Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique</title><title>Cancer Immunology, Immunotherapy</title><addtitle>Cancer Immunol Immunother</addtitle><description>The presence of circulating antineuronal antibodies has been associated with paraneoplastic neurological syndromes (PNS). Ri antibodies are often associated with lung or breast cancer, but the prevalence of such antibodies in large cancer materials is largely unknown. We used a highly sensitive immunoprecipitation assay to study the level of Ri antibodies in blood samples from 200 patients with small cell lung cancer (SCLC), 253 patients with breast cancer and 557 patients with ovarian cancer. Two hundred blood donors and six Ri positive PNS patients served as controls. The recombinant antigen used in the immunoprecipitation assay was radiolabeled by a coupled in vitro transcription and translation (ITT) technique, enabling low levels of antibodies to be detected. None of the blood donors contained Ri antibodies, whereas all of the sera from the PNS patients were positive. Ri antibodies were present in 4.5% of the patients with SCLC, 0.8% of the patients with breast cancer and in 0.2% of the patients with ovarian cancer. Retesting of the Ri positive samples with immunofluorescense and immune blot showed that the immunoprecipitation technique was more sensitive than the other immune assays. Ri antibodies were not associated with PNS in the patients with breast or ovarian cancer. Neurological data were not available for the SCLC patients, but in these, Ri antibodies were not associated with survival.</description><subject>Antibodies - blood</subject><subject>Antigens, Neoplasm - immunology</subject><subject>Antineoplastic agents</subject><subject>Biological and medical sciences</subject><subject>Blotting, Western</subject><subject>Breast Neoplasms - blood</subject><subject>Breast Neoplasms - immunology</subject><subject>Breast Neoplasms - mortality</subject><subject>Carcinoma, Small Cell - blood</subject><subject>Carcinoma, Small Cell - immunology</subject><subject>Female</subject><subject>Fluorescent Antibody Technique</subject><subject>Humans</subject><subject>Immunoblotting</subject><subject>Immunoprecipitation - methods</subject><subject>Immunotherapy</subject><subject>Lung cancer</subject><subject>Lung Neoplasms - blood</subject><subject>Lung Neoplasms - immunology</subject><subject>Lung Neoplasms - mortality</subject><subject>Medical sciences</subject><subject>Neoplasms - blood</subject><subject>Neoplasms - immunology</subject><subject>Neoplasms - mortality</subject><subject>Nerve Tissue Proteins - immunology</subject><subject>Neuro-Oncological Ventral Antigen</subject><subject>Original</subject><subject>Ovarian Neoplasms - blood</subject><subject>Ovarian Neoplasms - immunology</subject><subject>Ovarian Neoplasms - mortality</subject><subject>Paraneoplastic Syndromes - blood</subject><subject>Paraneoplastic Syndromes - diagnosis</subject><subject>Paraneoplastic Syndromes - immunology</subject><subject>Pharmacology. Drug treatments</subject><subject>Pneumology</subject><subject>RNA-Binding Proteins - immunology</subject><subject>Sensitivity and Specificity</subject><subject>Survival Analysis</subject><subject>Tumors of the respiratory system and mediastinum</subject><issn>0340-7004</issn><issn>1432-0851</issn><issn>1365-2567</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkk2LFDEQhoMo7rj6A7xIEPRkayXppDunRRa_YEEQPYfqdHonS3cyJumRvfnTzTCDq168JKHy1Et9vIQ8ZfCaAXRvMgBXvAFQDTDOGn6PbFgraqSX7D7ZgGih6QDaM_Io55v64KD1Q3LGVMu1YO2G_PziKYbihzh6l6kPdIfFu1Ay_eHLlg7JYS6vaNxj8hhoTDQvOM_UunrMa7imFoN1iY6uuLT44EY63FKk2YXsi9876pdlDXGXnPU7X6p8DLQ4uw3---oekwcTztk9Od3n5Nv7d18vPzZXnz98unx71di2V6VBK-zYqqkbuJyYRESpJ95Z6Uauez1hKxlqNijsrIDRql5pGLDvRIdyUE6ck4uj7m4dFjfa2mLC2eySXzDdmoje_P0T_NZcx71hDAQokFXh5UkhxVp4Lmbx-TAGDC6u2aheamCS_RfkwAUTWlXw-T_gTVxTqGMwnAl5wLoKsSNkU8w5uel3zQzMwQbmaANTbWAONjC85jz7s9m7jNPeK_DiBGC2OE-p7tDnO67TiguuxC-OSL2a</recordid><startdate>20061001</startdate><enddate>20061001</enddate><creator>KNUDSEN, Anette</creator><creator>MONSTAD, Sissel E</creator><creator>DORUM, Anne</creator><creator>LØNNING, Per E</creator><creator>SALVESEN, Helga B</creator><creator>DRIVSHOLM, Lars</creator><creator>AARSETH, Jan H</creator><creator>VEDELER, Christian A</creator><general>Springer</general><general>Springer Nature B.V</general><general>Springer-Verlag</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20061001</creationdate><title>Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique</title><author>KNUDSEN, Anette ; MONSTAD, Sissel E ; DORUM, Anne ; LØNNING, Per E ; SALVESEN, Helga B ; DRIVSHOLM, Lars ; AARSETH, Jan H ; VEDELER, Christian A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c486t-ac3cd46f7b25f15aaa59f27c5ed2989fa451a91b6a7c30dc68690ba8737a5b6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Antibodies - blood</topic><topic>Antigens, Neoplasm - immunology</topic><topic>Antineoplastic agents</topic><topic>Biological and medical sciences</topic><topic>Blotting, Western</topic><topic>Breast Neoplasms - blood</topic><topic>Breast Neoplasms - immunology</topic><topic>Breast Neoplasms - mortality</topic><topic>Carcinoma, Small Cell - blood</topic><topic>Carcinoma, Small Cell - immunology</topic><topic>Female</topic><topic>Fluorescent Antibody Technique</topic><topic>Humans</topic><topic>Immunoblotting</topic><topic>Immunoprecipitation - methods</topic><topic>Immunotherapy</topic><topic>Lung cancer</topic><topic>Lung Neoplasms - blood</topic><topic>Lung Neoplasms - immunology</topic><topic>Lung Neoplasms - mortality</topic><topic>Medical sciences</topic><topic>Neoplasms - blood</topic><topic>Neoplasms - immunology</topic><topic>Neoplasms - mortality</topic><topic>Nerve Tissue Proteins - immunology</topic><topic>Neuro-Oncological Ventral Antigen</topic><topic>Original</topic><topic>Ovarian Neoplasms - blood</topic><topic>Ovarian Neoplasms - immunology</topic><topic>Ovarian Neoplasms - mortality</topic><topic>Paraneoplastic Syndromes - blood</topic><topic>Paraneoplastic Syndromes - diagnosis</topic><topic>Paraneoplastic Syndromes - immunology</topic><topic>Pharmacology. Drug treatments</topic><topic>Pneumology</topic><topic>RNA-Binding Proteins - immunology</topic><topic>Sensitivity and Specificity</topic><topic>Survival Analysis</topic><topic>Tumors of the respiratory system and mediastinum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KNUDSEN, Anette</creatorcontrib><creatorcontrib>MONSTAD, Sissel E</creatorcontrib><creatorcontrib>DORUM, Anne</creatorcontrib><creatorcontrib>LØNNING, Per E</creatorcontrib><creatorcontrib>SALVESEN, Helga B</creatorcontrib><creatorcontrib>DRIVSHOLM, Lars</creatorcontrib><creatorcontrib>AARSETH, Jan H</creatorcontrib><creatorcontrib>VEDELER, Christian A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cancer Immunology, Immunotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KNUDSEN, Anette</au><au>MONSTAD, Sissel E</au><au>DORUM, Anne</au><au>LØNNING, Per E</au><au>SALVESEN, Helga B</au><au>DRIVSHOLM, Lars</au><au>AARSETH, Jan H</au><au>VEDELER, Christian A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique</atitle><jtitle>Cancer Immunology, Immunotherapy</jtitle><addtitle>Cancer Immunol Immunother</addtitle><date>2006-10-01</date><risdate>2006</risdate><volume>55</volume><issue>10</issue><spage>1280</spage><epage>1284</epage><pages>1280-1284</pages><issn>0340-7004</issn><eissn>1432-0851</eissn><eissn>1365-2567</eissn><coden>CIIMDN</coden><abstract>The presence of circulating antineuronal antibodies has been associated with paraneoplastic neurological syndromes (PNS). Ri antibodies are often associated with lung or breast cancer, but the prevalence of such antibodies in large cancer materials is largely unknown. We used a highly sensitive immunoprecipitation assay to study the level of Ri antibodies in blood samples from 200 patients with small cell lung cancer (SCLC), 253 patients with breast cancer and 557 patients with ovarian cancer. Two hundred blood donors and six Ri positive PNS patients served as controls. The recombinant antigen used in the immunoprecipitation assay was radiolabeled by a coupled in vitro transcription and translation (ITT) technique, enabling low levels of antibodies to be detected. None of the blood donors contained Ri antibodies, whereas all of the sera from the PNS patients were positive. Ri antibodies were present in 4.5% of the patients with SCLC, 0.8% of the patients with breast cancer and in 0.2% of the patients with ovarian cancer. Retesting of the Ri positive samples with immunofluorescense and immune blot showed that the immunoprecipitation technique was more sensitive than the other immune assays. Ri antibodies were not associated with PNS in the patients with breast or ovarian cancer. Neurological data were not available for the SCLC patients, but in these, Ri antibodies were not associated with survival.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>16429314</pmid><doi>10.1007/s00262-006-0121-2</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0340-7004 |
| ispartof | Cancer Immunology, Immunotherapy, 2006-10, Vol.55 (10), p.1280-1284 |
| issn | 0340-7004 1432-0851 1365-2567 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11030605 |
| source | Wiley Free Content; MEDLINE; Springer Nature - Complete Springer Journals; IngentaConnect Free/Open Access Journals; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Antibodies - blood Antigens, Neoplasm - immunology Antineoplastic agents Biological and medical sciences Blotting, Western Breast Neoplasms - blood Breast Neoplasms - immunology Breast Neoplasms - mortality Carcinoma, Small Cell - blood Carcinoma, Small Cell - immunology Female Fluorescent Antibody Technique Humans Immunoblotting Immunoprecipitation - methods Immunotherapy Lung cancer Lung Neoplasms - blood Lung Neoplasms - immunology Lung Neoplasms - mortality Medical sciences Neoplasms - blood Neoplasms - immunology Neoplasms - mortality Nerve Tissue Proteins - immunology Neuro-Oncological Ventral Antigen Original Ovarian Neoplasms - blood Ovarian Neoplasms - immunology Ovarian Neoplasms - mortality Paraneoplastic Syndromes - blood Paraneoplastic Syndromes - diagnosis Paraneoplastic Syndromes - immunology Pharmacology. Drug treatments Pneumology RNA-Binding Proteins - immunology Sensitivity and Specificity Survival Analysis Tumors of the respiratory system and mediastinum |
| title | Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T22%3A18%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Ri%20antibodies%20in%20patients%20with%20breast,%20ovarian%20or%20small%20cell%20lung%20cancer%20determined%20by%20a%20sensitive%20immunoprecipitation%20technique&rft.jtitle=Cancer%20Immunology,%20Immunotherapy&rft.au=KNUDSEN,%20Anette&rft.date=2006-10-01&rft.volume=55&rft.issue=10&rft.spage=1280&rft.epage=1284&rft.pages=1280-1284&rft.issn=0340-7004&rft.eissn=1432-0851&rft.coden=CIIMDN&rft_id=info:doi/10.1007/s00262-006-0121-2&rft_dat=%3Cproquest_pubme%3E68590151%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=213502317&rft_id=info:pmid/16429314&rfr_iscdi=true |