Immunosenescence: limitations of natural killer cell-based cancer immunotherapy

Cancer is primarily considered a disease of old age. Immunosenescence refers to the age-associated changes in the immune system, and its contribution to the increased risk of cancer in old individuals has been discussed for many years. Natural killer (NK) cells are cytotoxic innate immune cells spec...

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Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2017-02, Vol.66 (2), p.233-245
Hauptverfasser:	Tarazona, Raquel, Sanchez-Correa, Beatriz, Casas-Avilés, Ignacio, Campos, Carmen, Pera, Alejandra, Morgado, Sara, López-Sejas, Nelson, Hassouneh, Fakhri, Bergua, Juan M., Arcos, Maria Jose, Bañas, Helena, Casado, Javier G., Durán, Esther, Labella, Fernando, Solana, Rafael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer Research Focussed Research Review Humans Immunology Immunosenescence - immunology Immunotherapy, Adoptive - methods Killer Cells, Natural - immunology Ligands Medicine Medicine & Public Health Neoplasms - immunology Neoplasms - therapy Oncology
Online-Zugang:	Volltext
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