The repertoire of tumor-infiltrating lymphocytes within the microenvironment of oral squamous cell carcinoma reveals immune dysfunction

Background The role of tumor-infiltrating lymphocytes (TILs) in the immune remodeling of tumor microenvironments (TME) in oral squamous cell carcinoma (OSCC) remains controversial. In this study, we pursued a comprehensive characterization of the repertoire of TILs and then analyzed its clinical sig...

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Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2020-03, Vol.69 (3), p.465-476
Hauptverfasser:	Quan, Hongzhi, Shan, Zhongyan, Liu, Ziyi, Liu, Sixuan, Yang, Liu, Fang, Xiaodan, Li, Kun, Wang, Baisheng, Deng, Zhiyuan, Hu, Yanjia, Yao, Zhigang, Huang, Junhui, Yu, Jianjun, Xia, Kun, Tang, Zhangui, Fang, Liangjuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Research Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology CD20 antigen Clinical significance Female Flow cytometry Foxp3 protein Helper cells Humans Immune response Immunohistochemistry Immunology Interleukin 17 Lymphocytes Lymphocytes T Lymphocytes, Tumor-Infiltrating - immunology Male Medical prognosis Medicine Medicine & Public Health Microenvironments Mouth Neoplasms - genetics Mouth Neoplasms - pathology Oncology Oral cancer Oral squamous cell carcinoma Original Original Article Paraffin PD-L1 protein Peripheral blood Phenotypes Squamous cell carcinoma Tumor Microenvironment Tumor-infiltrating lymphocytes
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