Clinicopathological factors associated with tumor-infiltrating lymphocyte reactivity in breast cancer

Background The clinical significance of adoptive tumor-infiltrating lymphocyte (TIL) therapy has been demonstrated in many clinical trials. We analyzed the in vitro reactivity of cultured TILs against autologous breast cancer cells. Methods TILs and cancer cells were cultured from 31 breast tumor ti...

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Veröffentlicht in:	Cancer Immunology, Immunotherapy Immunotherapy, 2020-11, Vol.69 (11), p.2381-2391
Hauptverfasser:	Lee, Heejae, Kim, Young-Ae, Kim, Youngho, Park, Hye Seon, Seo, Jeong-Han, Lee, Hyun, Gong, Gyungyub, Lee, Hee Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic Agents - therapeutic use Cancer Research Chemotherapy, Adjuvant - methods Female Humans Immunology Lymphocytes, Tumor-Infiltrating - immunology Medicine Medicine & Public Health Middle Aged Neoadjuvant Therapy - methods Oncology Original Original Article Programmed Cell Death 1 Receptor - drug effects Programmed Cell Death 1 Receptor - metabolism Triple Negative Breast Neoplasms - drug therapy Triple Negative Breast Neoplasms - immunology Triple Negative Breast Neoplasms - pathology Tumor Cells, Cultured
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