Time course and magnitude of ventilatory and renal acid-base acclimatization following rapid ascent to and residence at 3,800 m over nine days

Rapid ascent to high altitude imposes an acute hypoxic and acid-base challenge, with ventilatory and renal acclimatization countering these perturbations. Specifically, ventilatory acclimatization improves oxygenation, but with concomitant hypocapnia and respiratory alkalosis. A compensatory, renall...

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Veröffentlicht in:	Journal of applied physiology (1985) 2021-06, Vol.130 (6), p.1705-1715
Hauptverfasser:	Bird, Jordan D, Leacy, Jack K, Foster, Glen E, Rickards, Caroline A, Wilson, Richard J A, O'Halloran, Ken D, Jendzjowsky, Nicholas G, Pentz, Brandon A, Byman, Britta R M, Thrall, Scott F, Skalk, Alexandra L, Hewitt, Sarah A, Steinback, Craig D, Burns, David, Ondrus, Peter, Day, Trevor A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acclimatization Acidosis Acids Alkalosis Altitude Ascent Bicarbonates Blood pressure Carbon dioxide High altitude High gain High-altitude environments Humans Hypocapnia Hypoxia Kidneys Metabolic acidosis Normalizing Oxygenation Perturbation
Online-Zugang:	Volltext
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