Sinonasal DLBCL: molecular profiling identifies subtypes with distinctive prognosis and targetable genetic features

•ABC and GCB subtype sinonasal DLBCL are geno- and phenotypically distinct entities, exhibiting a contrasting disease course and prognosis.•ABC subtype sinonasal DLBCL is part of a superordinate family of MCD lymphomas, presenting at immune-privileged and other extranodal sites. [Display omitted] Pr...

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Veröffentlicht in:	Blood advances 2024-04, Vol.8 (8), p.1946-1957
Hauptverfasser:	Eriksen, Patrick R. G., de Groot, Fleur, Clasen-Linde, Erik, de Nully Brown, Peter, de Groen, Ruben, Melchior, Linea C., Maier, Andrea D., Minderman, Marthe, Vermaat, Joost S. P., von Buchwald, Christian, Pals, Steven T., Heegaard, Steffen
Format:	Artikel
Sprache:	eng
Schlagworte:	Epstein-Barr Virus Infections Herpesvirus 4, Human - metabolism Humans Lymphoid Neoplasia Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - drug therapy Lymphoma, Large B-Cell, Diffuse - genetics Myeloid Differentiation Factor 88 - metabolism Neoplasm Recurrence, Local Prognosis Recurrence
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