A multivariate approach to understanding the genetic overlap between externalizing phenotypes and substance use disorders

Substance use disorders (SUDs) are phenotypically and genetically correlated with each other and with other psychological traits characterized by behavioural under‐control, termed externalizing phenotypes. In this study, we used genomic structural equation modelling to explore the shared genetic arc...

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Veröffentlicht in:	Addiction biology 2023-09, Vol.28 (9), p.e13319-n/a
Hauptverfasser:	Poore, Holly E., Hatoum, Alexander, Mallard, Travis T., Sanchez‐Roige, Sandra, Waldman, Irwin D., Palmer, Abraham A., Harden, K. Paige, Barr, Peter B., Dick, Danielle M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictions Behavior, Addictive Drug use externalizing Genetic diversity Genome-Wide Association Study genomic structural equation modelling Humans Phenotype Phenotypes Polygenic inheritance Reproducibility of Results Risk factors Structural equation modeling Substance use Substance use disorder substance use disorders Substance-Related Disorders - genetics
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