PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer

Colorectal cancer (CRC) remains one of the leading causes of cancer-related death worldwide. The poor prognosis of this malignancy is attributed mainly to the persistent activation of cancer signaling for metastasis. Here, we showed that protein tyrosine phosphatase-like A domain containing 1 (PTPLA...

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Veröffentlicht in:	International journal of biological sciences 2024-01, Vol.20 (6), p.2202-2218
Hauptverfasser:	Huang, Zi-Jia, Li, Yang-Jia, Yang, Jie, Huang, Lei, Zhao, Qian, Lu, Yi-Fan, Hu, Yang, Zhang, Wei-Xia, Liang, Jun-Ze, Pan, Jinghua, Pan, Yun-Long, He, Qing-Yu, Wang, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids Colonic Neoplasms Epithelial-Mesenchymal Transition - genetics Humans Mitochondrial Dynamics Research Paper Signal Transduction
Online-Zugang:	Volltext
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