Improving drug response prediction via integrating gene relationships with deep learning

Abstract Predicting the drug response of cancer cell lines is crucial for advancing personalized cancer treatment, yet remains challenging due to tumor heterogeneity and individual diversity. In this study, we present a deep learning-based framework named Deep neural network Integrating Prior Knowle...

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Veröffentlicht in:Briefings in bioinformatics 2024-03, Vol.25 (3)
Hauptverfasser: Li, Pengyong, Jiang, Zhengxiang, Liu, Tianxiao, Liu, Xinyu, Qiao, Hui, Yao, Xiaojun
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Sprache:eng
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