High-Throughput Interactome Determination via Sulfur Anomalous Scattering

We propose a novel approach for detecting the binding between proteins making use of the anomalous diffraction of natively present heavy elements, e.g., sulfurs, inside molecular three-dimensional structures. In particular, we analytically and numerically show that the diffraction patterns produced...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The journal of physical chemistry letters 2024-04, Vol.15 (13), p.3478-3485
Hauptverfasser:	Miotto, Mattia, Milanetti, Edoardo, Mincigrucci, Riccardo, Masciovecchio, Claudio, Ruocco, Giancarlo
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystallography, X-Ray Letter Models, Molecular Physical Insights into Materials and Molecular Properties Proteins - chemistry Sulfur - chemistry Synchrotrons
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!