Hereditary Creutzfeldt-Jakob Disease: A Case Presentation of a Rare Stroke Mimic
Acute ischemic cerebrovascular accident (CVA) is a time-sensitive emergent diagnosis, requiring rapid diagnosis and consideration of thrombolytic administration. However, a myriad of cerebrovascular mimics creates a diagnostic challenge. A rare CVA mimic is Creutzfeldt-Jakob disease (CJD), a rapidly...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-03, Vol.16 (3), p.e55559 |
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| creator | Bridwell, Rachel E Barlow, Jessica A Jacobson, Andrew R Curell, Angela Long, Brit |
| description | Acute ischemic cerebrovascular accident (CVA) is a time-sensitive emergent diagnosis, requiring rapid diagnosis and consideration of thrombolytic administration. However, a myriad of cerebrovascular mimics creates a diagnostic challenge. A rare CVA mimic is Creutzfeldt-Jakob disease (CJD), a rapidly progressive fatal dementia due to protein misfolding. Magnetic resonance imaging (MRI) and neurology consultation for electroencephalogram (EEG) and specialized cerebrospinal fluid (CSF) studies are diagnostic while the patient is alive. All forms are fatal within months, and diagnosis can be confirmed on postmortem brain testing. While incredibly uncommon, emergency clinicians should consider this diagnosis in the proper patient to advocate for specialized CSF testing and potential palliative care consultation. |
| doi_str_mv | 10.7759/cureus.55559 |
| format | Article |
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However, a myriad of cerebrovascular mimics creates a diagnostic challenge. A rare CVA mimic is Creutzfeldt-Jakob disease (CJD), a rapidly progressive fatal dementia due to protein misfolding. Magnetic resonance imaging (MRI) and neurology consultation for electroencephalogram (EEG) and specialized cerebrospinal fluid (CSF) studies are diagnostic while the patient is alive. All forms are fatal within months, and diagnosis can be confirmed on postmortem brain testing. 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| subjects | Ataxia Cerebrospinal fluid Creutzfeldt-Jakob disease Dementia Diagnostic tests Diplopia Electroencephalography Emergency medical care Emergency Medicine Etiology Family medical history Hospitals Iatrogenesis Infectious Disease Ischemia Magnetic resonance imaging Mutation Neurology Neurosurgery Patients Proteins Tomography Transplants & implants Trauma Visual acuity |
| title | Hereditary Creutzfeldt-Jakob Disease: A Case Presentation of a Rare Stroke Mimic |
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