Extracellular metallothionein as a therapeutic target in the early progression of type 1 diabetes

Type 1 diabetes (T1D) is characterized by lymphocyte infiltration into the pancreatic islets of Langerhans, leading to the destruction of insulin-producing beta cells and uncontrolled hyperglycemia. In the nonobese diabetic (NOD) murine model of T1D, the onset of this infiltration starts several wee...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cell stress & chaperones 2024-04, Vol.29 (2), p.312-325
Hauptverfasser:	Melchiorre, Clare K., Lynes, Matthew D., Bhandari, Sadikshya, Su, Sheng-Chiang, Potts, Christian M., Thees, Amy V., Norris, Carol E., Liaw, Lucy, Tseng, Yu-Hua, Lynes, Michael A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemokine CXCL12 Diabetes Mellitus, Type 1 - metabolism Diabetes Mellitus, Type 1 - prevention & control Humans Metallothionein - genetics Metallothionein - metabolism Mice Mice, Inbred NOD Prediabetic State Research Paper Research Papers
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!