Understanding the pharmacokinetic journey of Fc-fusion protein, rhIL-7-hyFc using complementary approach of two analytical methods, accelerator mass spectrometry and ELISA

Abstract Antibody-based therapeutics (ABTs), including monoclonal/polyclonal antibodies and fragment crystallizable region (Fc)-fusion proteins, are increasingly used in disease treatment, driving the global market growth. Understanding the pharmacokinetic (PK) properties of ABTs is crucial for thei...

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Veröffentlicht in:Antibody therapeutics 2024-04, Vol.7 (2), p.105-113
Hauptverfasser: Kim, Anhye, Oh, Min-Seok, Lee, Gwan-Ho, Song, Seongeun, Byun, Mi-sun, Choi, Donghoon, Yu, Byung-Yong, Lee, Howard
Format: Artikel
Sprache:eng
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