Bacteriophage-based particles carrying the TNF-related apoptosis-inducing ligand (TRAIL) gene for targeted delivery in hepatocellular carcinoma

The TRAIL (Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand) is a promising candidate for cancer treatment due to its unique ability to selectively induce programmed cell death, or apoptosis, in cancer cells while sparing healthy ones. This selectivity arises from the preferential binding of...

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Veröffentlicht in:	Nanoscale 2024-03, Vol.16 (13), p.663-6617
Hauptverfasser:	Sittiju, Pattaralawan, Wudtiwai, Benjawan, Chongchai, Aitthiphon, Hajitou, Amin, Kongtawelert, Prachya, Pothacharoen, Peraphan, Suwan, Keittisak
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Bacteriophages - metabolism Binding Cancer Cancer therapies Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - therapy Cell death Cell Line, Tumor Chemistry Gene therapy Genetic Therapy - methods Humans Ligands Liver cancer Liver Neoplasms - drug therapy Liver Neoplasms - therapy Phages Receptors Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics TNF-Related Apoptosis-Inducing Ligand - metabolism Tumor necrosis factor-TNF
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