Case weighted power priors for hybrid control analyses with time-to-event data

We develop a method for hybrid analyses that uses external controls to augment internal control arms in randomized controlled trials (RCTs) where the degree of borrowing is determined based on similarity between RCT and external control patients to account for systematic differences (e.g., unmeasure...

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Veröffentlicht in:	Biometrics 2024-03, Vol.80 (2)
Hauptverfasser:	Kwiatkowski, Evan, Zhu, Jiawen, Li, Xiao, Pang, Herbert, Lieberman, Grazyna, Psioda, Matthew A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayes Theorem Biometric Practice Computer Simulation Humans Proportional Hazards Models Research Design
Online-Zugang:	Volltext
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