BDNF and cAMP are neuroprotective in a porcine model of traumatic optic neuropathy

Traumatic optic neuropathy (TON) is a devastating condition that can occur after blunt or penetrating trauma to the head, leading to visual impairment or blindness. Despite these debilitating effects, no clinically available therapeutic targets neuroprotection or promotes axon regeneration in this o...

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Veröffentlicht in:	JCI insight 2024-02, Vol.9 (3)
Hauptverfasser:	Heng, Kathleen, Young, Brent K, Li, BaoXiang, Nies, Ashley D, Xia, Xin, Wen, Runxia R, Dalal, Roopa, Bramblett, Gregory T, Holt, Andrew W, Cleland, Jeffery M, Harris, Jason N, Wu, Albert Y, Goldberg, Jeffrey L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - metabolism Brain-Derived Neurotrophic Factor - metabolism Nerve Regeneration Neuroprotection Optic Nerve Injuries - drug therapy Swine Swine, Miniature - metabolism Vision Disorders
Online-Zugang:	Volltext
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