Multisite Mpox Infection and Viral Dynamics Among Persons With HIV in Metro Atlanta
The 2022 mpox outbreak primarily involved sexual transmission among men who have sex with men and disproportionately affected persons with human immunodeficiency virus (HIV). We examined viral dynamics and clinical features in a cohort evaluated for mpox infection at a comprehensive HIV clinic in At...
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| Veröffentlicht in: | The Journal of infectious diseases 2024-03, Vol.229 (Supplement_2), p.S213-S218 |
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| creator | Damhorst, Gregory L Fujita, A Wendy Fitts, Eric Szabo, Brittany Bowers, Heather B Sabino, Courtney Ahmed, Alaa Wang, Ethan Piantadosi, Anne McLendon, Kaleb Sullivan, Julie Greenleaf, Morgan McCaslin, Divine Palmore, Melody Anderson, Albert M Aldred, Bruce Gunthel, Clifford Martin, Greg S Colasanti, Jonathan A Lam, Wilbur A Bassit, Leda Rao, Anuradha Sheth, Anandi N Titanji, Boghuma K |
| description | The 2022 mpox outbreak primarily involved sexual transmission among men who have sex with men and disproportionately affected persons with human immunodeficiency virus (HIV). We examined viral dynamics and clinical features in a cohort evaluated for mpox infection at a comprehensive HIV clinic in Atlanta, Georgia. Viral DNA was found in 8 oropharyngeal and 5 anorectal specimens among 10 mpox cases confirmed by lesion swab polymerase chain reaction. Within-participant anatomic site of lowest cycle threshold (Ct) value varied, and lower Ct values were found in oropharyngeal and anorectal swabs when corresponding symptoms were present. This provides insight into mpox infection across multiple anatomic sites among people with HIV. |
| doi_str_mv | 10.1093/infdis/jiad530 |
| format | Article |
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We examined viral dynamics and clinical features in a cohort evaluated for mpox infection at a comprehensive HIV clinic in Atlanta, Georgia. Viral DNA was found in 8 oropharyngeal and 5 anorectal specimens among 10 mpox cases confirmed by lesion swab polymerase chain reaction. Within-participant anatomic site of lowest cycle threshold (Ct) value varied, and lower Ct values were found in oropharyngeal and anorectal swabs when corresponding symptoms were present. 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| source | MEDLINE; Oxford University Press Journals Current |
| subjects | Ambulatory Care Facilities HIV Infections Homosexuality, Male Humans Male Mpox (monkeypox) Sexual and Gender Minorities Supplement |
| title | Multisite Mpox Infection and Viral Dynamics Among Persons With HIV in Metro Atlanta |
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