Heat shock factor 1 drives regulatory T-cell induction to limit murine intestinal inflammation

The heat shock response is a critical component of the inflammatory cascade that prevents misfolding of new proteins and regulates immune responses. Activation of clusters of differentiation (CD)4+ T cells causes an upregulation of heat shock transcription factor, heat shock factor 1 (HSF1). We hypo...

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Veröffentlicht in:	Mucosal immunology 2024-02, Vol.17 (1), p.94-110
Hauptverfasser:	Collins, Colm B., Nguyen, Tom T., Leddy, Robert S., Alula, Kibrom M., Yeckes, Alyson R., Strassheim, Derek, Aherne, Carol M., Luck, Marisa E., Karoor, Vijaya, Jedlicka, Paul, Pierce, Anson, de Zoeten, Edwin F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Forkhead Transcription Factors - genetics Heat Shock Transcription Factors - genetics Heat-Shock Response Inflammation Mice Mice, Knockout Mice, Transgenic T-Lymphocytes, Regulatory
Online-Zugang:	Volltext
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