Retention of uninfected red blood cells causing congestive splenomegaly is the major mechanism of anemia in malaria

Splenomegaly frequently occurs in patients with Plasmodium falciparum (Pf) or P. vivax (Pv) malarial anemia, but mechanisms underlying this co‐occurrence are unclear. In malaria‐endemic Papua, Indonesia, we prospectively analyzed red blood cell (RBC) concentrations in the spleen and spleen‐mimetic r...

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Veröffentlicht in:	American journal of hematology 2024-02, Vol.99 (2), p.223-235
Hauptverfasser:	Kho, Steven, Siregar, Nurjati C., Qotrunnada, Labibah, Fricot, Aurélie, Sissoko, Abdoulaye, Shanti, Putu A. I., Candrawati, Freis, Kambuaya, Noy N., Rini, Hasrini, Andries, Benediktus, Hardy, David, Margyaningsih, Nur I., Fadllan, Fauziyah, Rahmayenti, Desandra A., Puspitasari, Agatha M., Aisah, Amelia R., Leonardo, Leo, Yayang, Bagus T. G., Margayani, Dewi S., Prayoga, Pak, Trianty, Leily, Kenangalem, Enny, Price, Ric N., Yeo, Tsin W., Minigo, Gabriela, Noviyanti, Rintis, Poespoprodjo, Jeanne R., Anstey, Nicholas M., Buffet, Pierre A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia Anemia - complications Erythrocytes Hematocrit Hematology Hemoglobin Humans Life Sciences Malaria Malaria - complications Malaria, Falciparum - complications Malaria, Vivax - complications Plasmodium falciparum Plasmodium vivax Red pulp Retention Spleen Splenomegaly Splenomegaly - etiology
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