Fascin-induced bundling protects actin filaments from disassembly by cofilin

Actin filament turnover plays a central role in shaping actin networks, yet the feedback mechanism between network architecture and filament assembly dynamics remains unclear. The activity of ADF/cofilin, the main protein family responsible for filament disassembly, has been mainly studied at the si...

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Veröffentlicht in:The Journal of cell biology 2024-06, Vol.223 (6), p.1
Hauptverfasser: Chikireddy, Jahnavi, Lengagne, Léana, Le Borgne, Rémi, Durieu, Catherine, Wioland, Hugo, Romet-Lemonne, Guillaume, Jégou, Antoine
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Sprache:eng
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