Mapping the T cell repertoire to a complex gut bacterial community

Certain bacterial strains from the microbiome induce a potent, antigen-specific T cell response 1 – 5 . However, the specificity of microbiome-induced T cells has not been explored at the strain level across the gut community. Here, we colonize germ-free mice with complex defined communities (roughl...

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Veröffentlicht in:Nature (London) 2023-09, Vol.621 (7977), p.162-170
Hauptverfasser: Nagashima, Kazuki, Zhao, Aishan, Atabakhsh, Katayoon, Bae, Minwoo, Blum, Jamie E., Weakley, Allison, Jain, Sunit, Meng, Xiandong, Cheng, Alice G., Wang, Min, Higginbottom, Steven, Dimas, Alex, Murugkar, Pallavi, Sattely, Elizabeth S., Moon, James J., Balskus, Emily P., Fischbach, Michael A.
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Sprache:eng
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