The Bulk Breast Cancer Cell and Breast Cancer Stem Cell Activity of Binuclear Copper(II)‐Phenanthroline Complexes

Mononuclear copper(II)‐phenanthroline complexes have been widely investigated as anticancer agents whereas multinuclear copper(II)‐phenanthroline complexes are underexplored. Here the synthesis and characterisation of two new binuclear copper(II)‐phenanthroline complexes 1 and 2 is reported, compris...

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Veröffentlicht in:	Chemistry : a European journal 2023-08, Vol.29 (45), p.e202301188-n/a
Hauptverfasser:	Osei, Priscilla B., Northcote‐Smith, Joshua, Fang, Jiaxin, Singh, Kuldip, Ortu, Fabrizio, Suntharalingam, Kogularamanan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antineoplastic Agents - pharmacology Antitumor agents antitumour agent Apoptosis artificial metallonuclease bioinorganic chemistry Breast cancer Breast Neoplasms - drug therapy cancer stem cell Cell Line, Tumor Chemistry Chlorides Cisplatin Coordination Complexes - pharmacology Copper DNA damage Female Humans Ligands Neoplastic Stem Cells Phenanthrolines - pharmacology Reactive oxygen species Salinomycin Stem cells Toxicity
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