Diagnosis and treatment of anti-insulin antibody-mediated labile glycaemia in insulin-treated diabetes

Anti-insulin antibodies in insulin-treated diabetes can derange glycaemia, but are under-recognised. Detection of significant antibodies is complicated by antigenically distinct insulin analogues. We evaluated a pragmatic biochemical approach to identifying actionable antibodies, and assessed its ut...

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Veröffentlicht in:	Diabetic medicine 2023-11, Vol.40 (11), p.e15194-e15194
Hauptverfasser:	Church, David S, Barker, Peter, Burling, Keith A, Shinwari, Shah K, Kennedy, Carmel, Smith, Diarmuid, Macfarlane, David P, Kernohan, Andrew, Stears, Anna, Karamat, Muhammad A, Whyte, Karen, Narendran, Parth, Halsall, David J, Semple, Robert K
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Blood glucose Decision making Diabetes Diabetes Mellitus Humans Hyperinsulinism Hypoglycemia Hypoglycemia - chemically induced Immunoassay Immunoreactivity Immunosuppression Insulin - therapeutic use Insulin Antibodies Insulin Resistance Ketoacidosis Lability Medical diagnosis Molecular weight Polyethylene glycol Research: Treatment
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