Head-mounted central venous access during optical recordings and manipulations of neural activity in mice

Establishing reliable intravenous catheterization in mice with optical implants allows the combination of neural manipulations and recordings with rapid, time-locked delivery of pharmacological agents. Here we present a procedure for handmade jugular vein catheters designed for head-mounted intraven...

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Veröffentlicht in:	Nature protocols 2024-03, Vol.19 (3), p.960-983
Hauptverfasser:	Liu, Christine, Freeman, Daniel J., Lammel, Stephan
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1689 631/378/1697 Analytical Chemistry Animal models Animals Biological Techniques Biomedical and Life Sciences Catheterization Catheters Computational Biology/Bioinformatics Drug delivery Head Intravenous administration Intubation Jugular vein Life Sciences Medical instruments Mice Microarrays Mouse devices Neural prostheses Optogenetics Organic Chemistry Pharmacology Photometry Prostheses and Implants Protocol Recording Survival Temporal resolution
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