TGFβ-induced long non-coding RNA LINC00313 activates Wnt signaling and promotes cholangiocarcinoma

Cholangiocarcinoma is a devastating liver cancer characterized by high aggressiveness and therapy resistance, resulting in poor prognosis. Long non-coding RNAs and signals imposed by oncogenic pathways, such as transforming growth factor β (TGFβ), frequently contribute to cholangiocarcinogenesis. He...

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Veröffentlicht in:	EMBO reports 2024-03, Vol.25 (3), p.1022-1054
Hauptverfasser:	Papoutsoglou, Panagiotis, Pineau, Raphaël, Leroux, Raffaële, Louis, Corentin, L’Haridon, Anaïs, Foretek, Dominika, Morillon, Antonin, Banales, Jesus M, Gilot, David, Aubry, Marc, Coulouarn, Cédric
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Biomedical and Life Sciences Cancer Cholangiocarcinoma Chromosomal Proteins, Non-Histone - metabolism DNA-Binding Proteins - metabolism EMBO03 EMBO36 EMBO37 Humans Life Sciences RNA, Long Noncoding - genetics Transcription Factors - metabolism Transforming Growth Factor beta - metabolism Wnt Signaling Pathway
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